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BOOK SUMMARY :

The discoveries highlighted in this book parallel the emergence of innovative molecular targeted small molecules and monoclonal antibodies ie agents that target proteins within highly activated stargeted drug strategies for cancer and inflammation editors jackman ann l leamon christopher p eds free preview describes the emerging range of therapeutics with the potential to more precisely target pathologic tissue recounts progress in the use of folates to transport antifolate drugs such as raltitrexed and pemetrexed that experimental design we first examined fr expression in an array of human ovarian cancer cell lines and then assessed the in vivo effect of morab 003 on tumor growth and progression in several orthotopic mouse models of ovarian cancer derived from these cell lines molecular mechanisms of tumor cell death induced by morab 003 were investigated by cdna and protein expression profiling analysisget this from a library targeted drug strategies for cancer and inflammation ann l jackman christopher p leamon the discoveries highlighted in this book parallel the emergence of innovativemolecular targeted small molecules and monoclonal antibodies ie agents that target proteins within highly activated read targeted drug strategies for cancer and inflammation by available from rakuten kobo folate pathways are essential in metabolism and macromolecule synthesis antifolate drugs that are largely transported v

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